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Aristocort (Triamcinolone)

Description

Aristocort - a synthetic hormone drug, glucocorticosteroid based on the main active substance - triamcinolone.

Aristocort has a pronounced anti-inflammatory, anti-allergic and immunosuppressive effect, in its effect similar to cortisone medication.

In terms of an anti-inflammatory effect of Aristocort is 1.5-2 times more efficient Prednisolone. A highly active glucocorticosteroid drug is better tolerated than other steroids, it has less mineralocorticoid action, the delay of sodium in blood is low, therefore, the preparation does not increase blood pressure and does not cause swelling. Hypoglemic and hyperglycemic effect is less pronounced, has little effect on protein metabolism. Osteoporosis typically does not affect the treatment regimen.

Aristocort acts strongly and quickly: the reaction in patients with acute rheumatic fever occurs within 48 hours, while lymphosarcoma, chronic and acute leukemia therapeutic effect is manifested in the 7-14 day of illness.

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Indications for use of the drug triamcinolone

Rheumatoid disease and collagen acute bursitis, rheumatism, (including infection), rheumatoid arthritis, gout, diffuse systemic lupus erythematosus (SLE);

Allergic diseases and acute allergic reactions;

Emphysema, pulmonary fibrosis, bronchial asthma in severe form, vasomotor rhinitis;

Hemorrhagic diathesis;

Diseases of the blood and lymphatic system: lymphoma, lymphosarcoma, acute and chronic leukemia;

Inflammatory diseases of the eye.

Diseases of the skin;

Administration regimen

The dose and frequency of Aristocort reception is determined by the physician depending on the disease, the drug is prescribed periorally and externally.

The usual regimen: the medication is appointed periorally; in adults - at 0,008-0,020 g per day in 3-4 receptions, preferably during or after meals. To press for a clinical effect the drug is consumed every 2-3 days at a daily dose of 0.002 g of, reduced until a minimum effective set maintenance dose, which in most cases amounts to 0.001-0.002 g

When lupus erythematosus, dermatomyositis, and pemphigus triamcinolone prescribed in doses of up to 0.03-0.05 g or more per day, while supporting doses range from 0,004 to 0,012g, after the stabilization process of the preparation is gradually canceled, instead assigning other symptomatic agents.

Patients with psoriatic arthritis and psoriatic erythroderma undergo short-term treatment of triamcinolone in cases of ineffectiveness of other drugs and heavy condition of the patient. The last 5-7 days of treatment and 3-4 days after discontinuation of the drug ACTH is administered in the dosage of 10 units twice a day.

Side effects & precautions

After administration of large doses of the preparation complications are sometimes observed by the type of cortisone, but unlike other corticosteroid medications it does not cause edema, potassium imbalance or increased appetite.

Occasionally seizures, weakness, myopathy, insomnia, mental disorders, exacerbation of infectious diseases, erosion and ulcer disease of the gastrointestinal tract, impaired vision, allergic reactions.

Do not use the medication with myasthenic syndrome and vegetative neurosis, osteoporosis. Aristocort application during pregnancy is contraindicated. In case of reception of the drug during lactation period breast-feeding should be discontinued.

The preparation must be appointed with caution with psychosis background.

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