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Benadryl (Diphenhydramine)


Benadryl is one of the main representatives of the group of antihistamines. It has an expressed antihistamine activity, provides a sedative and anticholinergic pharmacological effect. It has a broncholytic action, relaxes smooth muscles of bronchi and ganglia, inhibits cough reflex, reduces edema of the mucous membrane of bronchi especially by the allergic asthma. The proper use of the dosage can provide a slight soporific and antiemetic reflex. A powerful and fast onset of the pharmacological action guarantees a maximal effect in a short period of time.

Directions for the use

- hives

- pollinosis

- vasomotorrhinitis

- itching dermatoses

- allergic conjunctivitis

- Quincke's disease

- serum disease

- allergic complications during medical therapy

- a complex therapy of anaphylactic shock, bronchial asthma, gastric ulcer

- major traumas of the skin and soft tissues (burns, crush injury)

A broad use of this drug in medical practice is possible due to the inhibition of the most important receptors which affect the appearance and increase of the allergic symptoms.

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Benadryl is prescribed both adults and children. Initially, a doctor should examine your disease and find out an exact type of the allergy and your sensitivity to the components of the drug. Also, if possible it is necessary to determine a hypothetical cause of the allergy in order to reduce factors influencing on the relapse of the disease. The dosage is indicated individually depending on the age of the patient, and his/her general clinical condition.

- a daily dose of Benadryl for children over 12 years old and adults is 25-50 mg every 4-6 hours

- children under 12 years old are prescribed 12.5-25 mg every 4-6 hours

- the dosage can be adjusted by your doctor depending on your sensitivity to the action of the drug

- the length of the treatment is 5-15 days


- contraindications for the use of the drug: hypersensitivity, age under 3 years old, pregnancy, period of lactation

- use limitations: narrowangle glaucoma, prostatic enlargement, and stenosis of neck of the urinary bladder. If these diseases are present, consult a doctor before taking Benadryl.

- It increases and prolongs the action of opiates and depressants such as alcohol, Phenobarbital, and drugs of the benzodiazepine series. It is necessary to exclude the same use of these components.

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