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Betapace (Sotalol)

Description

Treating cardiac arrhythmia and the resulting ailments such as hypertension, myocardial infarction can be effective with the use of a number of drugs beta-blockers. One of the most prominent drugs in this group is Betapace, finding itself comfortably among the alternatives because of the pronounced effect on the sub-processes in the body, thereby helping the body fight the disease.

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Pharmacological action

The drug has antiarrhythmic and hypotensive effect, reduces the level of Ca2 (calcium in the cell membrane of the organism), and removes the signs of coronary insufficiency. The main component of sotalol reduces the excitability of the myocardium and normalizes heart rate. The systematic use of the drug leads to the achievement of hypotensive effect, ie, reducing blood pressure to a normal figure, adjusted bloodstream walls of the atria. In hypertension, achieving a positive effect occurs after only 2-4 days of regular use. Betapace also contributes to enhanced oxygen metabolism in tissue and eliminates the main reasons for arrhythmia increased pressure on the walls of blood vessels, and circulatory disorders, including, nervous excitability. The drug has positive characteristics as an effective tool for the treatment of complex cardiovascular pathologies at different stages of development.

Indications

The drug is often prescribed for supraventricular arrhythmias and appointed in chronic or symptomatic cardiac arrhythmias.

Contraindications

The medication must not bae taken in the following cases:

- IIB-III stage chronic heart failure;

- cardiogenic shock;
- hypotension;
- AV-block (grade II or III);
- weak sinus syndrome;
- sinoatrial block;
- bradycardia;
- obliterating vascular disease;
- asthma;
- acute form of myocardial infarction;
- metabolic acidosis;
- renal insufficiency;
- a severe form of allergic rhinitis;
- lactation;
- Hypersensitivity to sulfonamides;
- under 18 years old.

Appointing the drug to those suffering from diabetes, psoriasis, patients with impaired kidney function, myocardial infarction, hypomagnesemia, hypokalemia, depression and elderly people should be made with caution. The active ingredient inhibits sensitivity to stimuli, so before using the medication the patient must be thoroughly tested for allergic reactions to the drug. With great care during pregnancy is appointed.

Overdose

In case of overdose the following symptoms can be observed: mydriasis, weakness, loss of consciousness, hypotension, bradycardia, bronchospasm, ventricular tachycardia,hypoglycemia, heart failure. Treatment is urgent gastric lavage, hemodialysis (cleansing of the blood), the appointment of activated carbon.

Special notes

It is necessary to monitor patients taking betaxolol, which should include monitoring of heart rate and blood pressure (once every 3-4 months after the initiation of a treatment course), glucose in patients with diabetes (once every 4-5 months), requires monitoring of renal function in elderly patients (one every 4-5 months). The patients must learn how to calculate heart rate and seek for medical attention in case of less than 50 beats/min heart rate. Abrupt cessation should be avoided, in those suffering from coronary heart disease especially. It is recommended to gradually reduce the dose, i.e. within 1-2 weeks and if necessary can simultaneously begin replacement therapy to prevent the progression of angina.

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