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Cefotaxime (Claforan)


The number of antibiotics, existing for today, is uncountable. Cefotaxime - is one of them.

The medication relates to a third generation cephalosporin antibiotic. This is a very powerful drug, used in the treatment of serious infectious diseases, passing in the internal organs in the respiratory tract, urinary system. In medical practice it is allowed to use in the treatment of people with immunodeficiency.

Cefotaxime comes in powder form to perform injections. The package contains only one single dose. So, you already knew that this antibiotic is used only as an injection.

This medicine not simply suspends the development of pathogenic microbes, the drug destroys the pathogen. It is active against a large number of pathogenic microorganisms. Among them there are germs that are resistant to other cephalosporins.

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How does Cefotaxime drug work?

Thirty minutes after injection in the body is observed the highest drug concentration. Cefotaxime is very well distributed to all organs and tissues. The remedy can pass the blood brain barrier, that is why, it is frequently used for the treatment of meningitis. More cefotaxime accumulates in the respiratory tract, in the cerebrospinal fluid, musculoskeletal system, skin, internal organs. A certain amount of the medication is processed in the liver, evacuating from the body in urine.

When you should use Cefotaxime and in what doses?

If you suffer from an infectious disease of the respiratory organs, organs of the ear - nose - throat , infections of the genitourinary system (including gonorrhea and chlamydia), you can turn for the help to Cefotaxime. If you suffer from various infectious diseases of the digestive organs, blood poisoning, endocarditis, meningitis , in these cases, the remedy is prescribed by qualified doctor. Infectious lesions of the joints or bones, as well as the dermis and muscle tissue, with infectious diseases of reproduction are also treated with this antibiotic. Cefotaxime can be combined with other antibiotics. It shows the highest activity in the treatment of infectious lesions of the skin and soft tissue - up to one hundred percent and in the treatment of meningitis - ninety-five percent.

What are the dosages? The dosage depends on the severity of the disease, the condition of the patient. Drug is used intravenously or intramuscularly. Injections are performed every twelve hours when no serious infectious disease. In complicated cases, allowed to reduce the intervals between injections to eight hours, and in severe cases, up to six hours.

Cefotaxime contraindications and precautions

The medical remedy is not used in the treatment of pregnant women in the first trimester of pregnancy, who are hypersensitive to antibiotics, as well as in patients with renal insufficiency. When using the drug, side effects are very rare and pass immediately after drug withdrawal.

Is it possible to give Cefotaxime to children?

Not every drug can be applied by young people and especially newborns. But cefotaxime is among the drugs that can be taken even by newborns.

When using cefotaxime in treating kids, you need to know the following features. It is delayed for a longer period than in the adult. For children, aged between one day and seven, the amount of the drug is equal to fifty milligrams per kilogram of body weight. This amount should be divided in half and administer intravenously in the morning and evening. If your child has already turned two weeks, but had not yet turned two months, the amount is fifty to one hundred milligrams per kilogram of body weight. This amount should be divided into three parts: morning, afternoon and evening. Infants whose body weight reaches five pounds, cefotaxime can be applied intravenously and intramuscularly in an amount of from fifty to one hundred milligrams per kilogram of body weight, divided into three or four doses.

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