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Celecoxib is the active ingredient in the drug with brand name Celebrex. This drug is available in the form of oral capsules with strengths of 50 mg, 100 mg, 200 mg, and 400 mg. The inactive ingredients present in Celebrex include povidone, edible inks, lactose monohydrate, croscarmellose sodium, magnesium stearate, sodium lauryl sulfate and gelatin
There are risks associated with the consumption of Celebrex. Hence the benefits are weighed against the risks and appropriate dosages are taken. Celebrex should be taken for the shortest duration possible with the lowest dosage possible to avoid any adverse effects. The dosage for the patients might vary according to the condition of the patient.
Celebrex is used in the treatment of Osteoarthritis, Rheumatoid Arthritis, Juvenile Rheumatoid Arthritis, Ankylosing Spondylitis, Acute Pain, Primary Dysmenorrhea, and Familial Adenomatous Polyposis.
For the treatment of Osteoarthritis a dosage of 200 mg per day is recommended. You can split this dosage into two doses of 100 mg each. For treating Rheumatoid Arthritis the recommended dosage might vary from 100 mg to 200 mg depending on the condition of the patient. This dosage can be given as a single dose or two doses daily. In the treatment of Juvenile Rheumatoid Arthritis the recommended dosage depends upon the weight of the patient. A dose of 50 mg is given twice daily for patients who are between 10 kg and 25 kg. The dose is 100 mg twice daily for patients whose weight is greater than 25 kg. For the treatment of Ankylosing Spondylitis 200 mg is given as a single dose or split into two doses of 100 mg each. If the patient is not responding to this dose of 200 mg per day even after six weeks, you might consider revising the dosage upwards to 400 mg per day. Even if there is no proper response to this dosage you have to look for alternative treatments. In treating acute pain 400 mg per day as single dose or two doses of 200 mg is recommended. On the first day an additional dosage of 200 mg might be recommended if the pain intolerable.
Celebrex comes under the NSAID (non steroidal anti inflammatory drug) category. These drugs are capable of increasing the risk of cardiovascular diseases in the patients. If the patient is already suffering from cardio ailments it is not advisable to give them Celebrex. Gastrointestinal events like ulceration, perforation of stomach, and bleeding might also occur that might be serious enough to be fatal. People with hypertension, renal infections, and women who are pregnant should not take this medication.
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