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Colchicine is a drug that is used as an anti-inflammatory. This drug is available in two strengths of 0.5 mg and 0.6 mg. Colchicine is used in the treatment of acute gouty arthritis. This drug is also taken to prevent further attacks of arthritis. At the first sign of discomfort the patient can take Colchicine so that the attack is prevented. This drug is packaged in bottles of 100.
In the treatment of acute gouty arthritis a dose of 1 mg or 1.2 mg is recommended. Every hour a unit of that drug is taken or two units are taken every two hours until the pain subsides. It is always better to have that drug in handy so that the patient can take that drug at the first instant of feeling the attack. After the initial dose the patient can take 0.5 mg or 0.6 mg at certain intervals like three hours. If the patient experiences diarrhea then the medicine should be stopped. It is necessary that the patient stop the dose before diarrhea sets in. In due course the patient will know when to stop that dose so that diarrhea is prevented. To control pain usually a total dosage of about 4 to 8 mg of Colchicine is necessary.
One of the severe side effects of using this drug is bone marrow depression. With this condition the bone marrow might not produce the required amount of blood cells. Patients might find decreased granulocytes, those cells that are key to fighting microorganisms. Inflammation of the nerves, bleeding within the skin, loss of hair, myopathy (disease of the muscles) and azoospermia (a condition where no sperm is found in the ejaculate) are some of the other side effects of using Colchicine.
Colchicine is interrupted by acidifying agents and the alkalinizing agents give the opposite effect.
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