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Decadron (Dexamethasone)


The active ingredient of Decadron is dexamethasone - glucocorticosteroid hormone secreted by the adrenal cortex. This substance is involved in the metabolism of sugars and proteins in the body. Its use provides a strong anti-inflammatory effect. In addition, adrenal cortex hormone is effective against allergic reactions. The preparation is appointed to those with strong and sharp decreases in blood pressure, shock reaction in the presence of a strong focus in the body of pathogenic organisms and strong toxicosis in the last trimester of gestation, when there is an urgent need to remove an allergic reaction (swelling of the upper respiratory).

This drug is available as a solution for injection, eye drops, ointments for the treatment of eye in the form of tablets. The dosage is adjusted depending on the severity of the disease. This could be from a half to fifteen milligrams milligrams per day. The full amount of the drug is given in two - three steps. If the dose is not large, dexamethasone can be taken once a day, preferably in the morning. With long-term use of this drug the development of side effects and disruption of the whole organism may be triggered. Thus, for example, osteoporosis may develop (because the body derives calcium during the course, and calcium is poorly digested with food. Therefore, if a patient is treated with Decadron for a long time, it is necessary to use calcium in the form of dietary supplements.

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Indications for use

The preparation is prescribed in Addison-Biermer disease, acute and subacute thyroiditis, hypothyroidism, progressive ophthalmopathy associated with hyperthyroidism, leukemia, lymphosarcoma, bronchial asthma, serum sickness, dermatitis, rheumatism, infectious-allergic arthritis and aplasia hypoplasia of hematopoiesis, agranulocytosis.

Dosage regimen

Higher doses of Decadron are used in case on the early stages of disease or during its acute forms. If a response is reduced dosage at intervals of several days to reach the maintenance dose or before the termination of treatment.

The dosage regimen is picked up individually. In severe cases, the early treatment implies the dosage of 10-15 mg per day, while the maintenance dose ranges from 2 to 5 mg daily. In acute asthmatic conditions and allergic diseases 2-3 mg of medication daily is applied during up to 2 weeks. In adrenogenital syndrome treatment the dose is selected according to the excretion of 17-ketosteroids in urine. Typically, the effect is achieved when the dose of 1-1.5 mg is appointed. The average daily dose of 2-3 mg is divided into several intakes with 2-3 hours breaks. In the treatment with small doses the drug is prescribed to be taken once a day in the morning.

Decadron side effects & special instructions

The side effects are increased appetite, weight gain, moon face, hirsutism, osteoporosis, increased intraocular pressure, long-term treatment, adrenocortical insufficiency, euphoria, irritability, sleep disturbances, increased blood pressure, ulcerogenic action, decreased immunity, exacerbation of chronic infections, menstrual disorders and the diabetes development.

The list of contraindications includes acute and chronic infections, viral diseases, acute psychosis, peptic ulcer and duodenal ulcer, diabetes, severe obesity.

Special instructions

During infectious diseases treatment the pills should be administered in conjunction with antimicrobial drugs, in peptic ulcer disease - with anti-ulcer agents. With adrenal insufficiency development, in cases requiring an additional load on the adrenal glands (trauma, surgery, etc), the dose is increased.

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