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Ditropan (Oxybutynin)


Urinary incontinence (enuresis) - found in almost every fifth person on the planet and occurs in people of all ages. Kids are more likely to suffer from enuresis. At the average age, the most of the patients - the fair sex, after forty, the share of men is increasing dramatically.

Doctors distinguish the following types of urinary incontinence:

- Imperative (urgent) - urination occurs spontaneously, the patient can not hold urine;

- Stress - leakage of urine occurs during physical exertion, sneezing, cough;

- Mixed - symptoms of the two previous options.

Only in the United States, incontinence is the disease of more than 10 million men.

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Treatment of enuresis with Ditropan

Urgent form of incontinence amenable to medical treatment. Usually, there are used drugs that relax the muscles of the bladder and prevent its spontaneous contractions at the same time.

Anticholinergic drugs, among which and Ditropan (oxybutynin), is the first line treatment therapy.

"Gold standard" in the treatment of children neurology of hyperactive bladder currently remains the drug oxybutynin (Ditropan). Oxybutynin is a drug with a mixed mechanism of action: other than anticholinergic activity (interruption of the efferent nerve impulses to the bladder at the level of post-ganglionic parasympathetic receptors), it has antispasmodic and local anesthetic action.

Ditropan information: indications and contraindications for use

Ditropan is indicated for the treatment of urinary tract disorders, like enuresis, hyperactive bladder syndrome, neurogenic bladder. This medication is used to treat diseases in patients of all ages.

To effectively treat hyperactive bladder syndrome, it is necessary to know its causes. In the appointment of Ditropan, the doctor should be notified, whether the patient has chronic diseases and after, he will inform you contraindications to the drug:

* Open-and closed-angle glaucoma;

* Obstruction of the gastrointestinal tract, intestinal obstruction;

* Ulcerative colitis;

* Myasthenia gravis;

* Obstructive uropathy;

* Bleeding;

* Children's age (under 5 years);

* Pregnancy, lactation.

Dosing regimen of Ditropan and side effects

Ditropan is taken at 5mg of more than 4 times a day. The average daily intake for adults is 15mg, for children - 10mg. Elderly patients a doctor may prescribe a lower dose of the drug and its subsequent gradual increase.

Patients, who participated in Ditropan clinical studies, informed about side effects, like:

- dyspepsia (nausea, vomiting, constipation, flatulence)

- dry mouth

- urinary disorders (including urinary retention)

- decreased motility of the stomach and intestines

- drowsiness or insomnia

- weakness

- dizziness

- anxiety

- allergic reactions.

Clinical studies results of Ditropan

The drug oxybutynin, having M-anticholinergic and antispasmodic action, is effective for the treatment of overactive bladder in children. To achieve the desired effect in some cases it is advisable to combine the use of Ditropan with metabolic therapy. In severe hypertension, that therapy should precede the appointment of oxybutynin to increase the sensitivity of M-cholinergic receptors. In order to predict the effect of the treatment and control of its dynamics, it is desirable to provide uroflometry with oxybutynin. To achieve a stable relief of enuresis in children with hyperactive bladder syndrome, the treatment courses with Ditropan should be repeated every 2 months or the appointment of oxybutynin should be prescribed for 10 days a month during 3 months.

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