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Doxazosin is a generic name of a medication that relaxes muscles in the blood vessels of the bladder and prostate and, thus, decreases the blood pressure. The drug is primarily used to treat men with enlarged prostate (benign prostatic hyperplasia), and it is also used to help people with hypertension (high blood pressure). In addition to that, it has been found, although not yet fully explained, that Doxazosin can help decrease stress and fight nightmares.

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Precautions and Contraindications

The drug is supposed to be taken orally (it is produced in tablets) once a day, usually with breakfast, but it can be taken at any time that is better for you Ė the most crucial is to take tablets at the same time each day. The tablets are swallowed with little water. It is highly important to consult a medical specialist before taking the drug to determine the right dosage for you and then take it exactly as suggested, as it can sometimes lower the pressure dramatically and make you feel light-headed or pass out. Donít change the dosage yourself. Donít drink alcohol while using the medicine as it will intensify possible side effects. You also have to avoid standing up suddenly from sitting and especially lying positions and get a doctor to check your pressure on a regular basis.

Doxazosin should be kept in a dry place in cool temperature of 10-25 C.

As the medicine can affect your pressure and make you experience dizziness, you have to be cautious when driving, operating dangerous equipment or doing any other things that require attention. For the same reason be sure to let your doctor know that youíre using Doxazosin before surgery, especially on eyes. Inform a specialist about any drugs, especially painkillers, youíre taking at the same time with Doxazosin as they can interact with it decreasing its efficiency and increasing side effects.

Pregnant or breastfeeding women should not take Doxazosin. Women who want to become pregnant should not use the drug either. There are other conditions you have to tell your health care provider about such as liver diseases, problems with heart, allergy to any medicine or in case you faint or feel dizzy after urinating.

Drug Interactions

There were no formal studies conducted about Doxazosin interactions with other drugs. However, clinical trials showed that there isnít any evidence of serious interactions with beta-blocking agents, nonsteroidal anti-inflammatory medications, warfarin, digoxin, phenytoin, indomethacin and thiazide diuretics. On the other hand, if taken together with oral cimetidine, the level of Doxazosin is slightly increasing and the level of serum rises by 10%. If taken with phosphodiesterase-5 inhibitors, Doxazosin may cause hypotension due to increase of its effectiveness in lowering blood pressure.

Therefore, it is recommended to inform a medical specialist about all the drugs youíre using at the same time with Doxazosin, and certain drugs in particular: antidepressants, medications that treat AIDS or HIV, drugs that treat impotence such as Viagra (sildenafil) or Cialis (tadalafil), antibiotics, etc. Even herbal treatments and vitamins may affect the way Doxazosin works.

Side Effects

You may notice several adverse effects while taking Doxazosin such as dizziness, light-headed feeling, unusual tiredness or drowsiness. These symptoms are not dangerous. The signs that should worry you are if you pass out, have stomach pain, pain in the chest, difficulty breathing or everlasting erections (more than four hours). Then you have to contact a medical specialist as soon as possible. In case of allergic reactions call emergency at once.

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