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Mestinon (Pyridostigmine)


Mestinon is a prescription medication used to strengthen the muscles and prevent the breakdown of natural substances in muscular diseases. Particularly, the drug prevents the breakdown of acetylcholine which is a substance that plays an important part in the transmission of messages from the nerves to the muscles. In muscular diseases like myasthenia gravis, the excessive breakdown of acetylcholine results to inadequate signal transmission which results to improper muscular function. With this medication, breakdown of acetylcholine is prevented and normal signal transmission of nerve impulses is maintained.

Mestinon is classified as an active cholinesterase inhibitor and is available in various forms. It can be given as a syrup which contains 60 mg of pyridostigmine bromide for each teaspoon. The medication is also available in tablet form.

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The drug is primarily recommended for patients suffering from myasthenia gravis. However, it is also recommended for patients suffering from paralytic ileus and post operative urinary retention. It is recommended for patients with these conditions and those who have not shown any allergic reactions to the drug or its ingredients. However, it is not recommended for patients suffering from mechanical obstructions in the intestines. Medical supervision is also recommended when used by patients with bronchial asthma.

Patients are required to tell their doctor about any allergic reactions to minimize the risk of hypersensitivity reactions. The liquid formulations may contain sugar or alcohol therefore patients are advised to be cautious if they are diabetic or have a history of alcohol abuse.

Side Effects

The most common side effect of Mestinon are nausea, vomiting, diarrhea and abdominal cramps. Some users may also experience increased urination and increased sweating. These last two symptoms should be taken seriously and immediate medical attention is needed once these symptoms are observed.

Other serious side effects include muscle cramps, shortness of breath, and weakness. Muscle weakness may be a sign of cholinergic crisis which happens in overdosage. In cases like these, withdrawal of the drug is the first step in treatment. Other users will also experience symptoms of an allergic reactions like rashes, itching, irritation and difficulty swallowing. Shortness of breath and chest pains are symptoms of a severe reaction and requires immediate medical attention.

Most doctors prescribe atropine to combat most of the side effects that accompany the use of Mestinon. Atropine has been found to effective in eliminating GI side effects. However, the use of atropine should also be strictly monitored, since the drug can also induce a cholinergic crisis.

The drug has not been extensively studied for its safety when used by pregnant women or lactating mothers. It is therefore recommended to use the drug in lower doses and to determine whether the benefits outweigh the risk before the drug is prescribed to pregnant or lactating patients. The drug may also be contraindicated in patients with moderate to severe renal diseases since the medication is excreted mainly through the kidneys and therefore the failure to excrete the drug can lead to toxicity. Older patients may be at a greater risk for side effects because of this.

How and Where to Purchase Online

Mestinon is available in most online pharmacies, but it is important to make sure that you are getting the medication from a trusted source. Registered and legitimate pharmacies that operate online are licensed to operate in the state. To make sure check your local state boards and see if the pharmacy is listed. State-licensed pharmacies are accessible through the state boards, and you can determine whether or not an online store is legitimate or not. These pharmacies may also require a a doctor's prescription before selling the medication. Professional and real pharmacies also offer customers a phone number that they call in case they have questions or in cases where there are other customer service concerns.

It is important to know how to shop for this medication online since there are hundreds, if not thousands, of fake pharmacy stores that sell placebos, fake medications, or medications with incorrect dosages. Intake of a drug which does not have the right formulation of active ingredients or the right dosage can lead to various side effects and may even become lethal. It is important to make sure that the drug is FDA-approved and dispensed by a licensed pharmacist.

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