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Prednisone Deltasone is one of the synthetic corticosteroid drugs; this drug is taken orally but can be delivered by intramuscular injection and can be used in different situations. It mainly works with the Glucocorticoid. Prednisone Deltasone when administered is converted to prednisolone by the liver; this prednisolone is the active drug and also a steroid.
Prednisone Deltasone is on the whole useful as an immunosuppressant. More over it affects almost entire immune system. Due to this property it is been used for the treatment of autoimmune diseases and inflammatory diseases.
The inflammatory diseases which are treated with Prednisone Deltasone are some forms of severe allergies, systemic lupus erythematosus, rheumatoid arthritis, Bell's Palsy, Crohn's disease, ulcerative colitis, pemphigus sarcoidosis and severe poison ivy dermatitis.
Prednisone Deltasone can also be used for the treatment of uveitis, kidney diseases such as nephrotic syndrome, mononucleosis and is also useful in preventing and treating organ rejection in organ transplantation. This drug has the ability to reduce sex drive, and help in the treatment of migraine headaches, cluster headaches and for severe Aphthous ulcer outbreaks.
It is famously used as an antitumor drug. This drug has shown a lot of success with the treatment of lymphoblastic leukemia in the acute stages, Non-Hodgkin's lymphomas, multiple myeloma, and other tumors in combination with other anticancer drugs. The other uses of Prednisone Deltasone are the treatment of the Jarisch-Herxheimer Reaction which is common during the treatment of syphilis, and to delay the onset of symptoms of Duchenne's muscular dystrophy.
Addiction: If Prednisone Deltasone is taken for more than seven days adrenal suppression will occur and the body will lose the ability to synthesize natural corticosteroids and as a result dependence on Prednisone Deltasone increases. Hence, Prednisone Deltasone should never be stopped immediately after taking it for more than 7 days but the dosage should be reduced gradually. If the use of Prednisone Deltasone is not taken on a long term treatment it may take a few days to reduce the drug, however if it is taken for a very long time than it may take weeks or months for the patient to come back to normal. However, if Prednisone Deltasone is abruptly stopped after taking it for more than seven days may lead to an Addisonian crisis, which may be life threatening.
Side-effects: High blood glucose levels is one of the side effect of this drug, if the person is already a diabetes mellitus patient or is on other medications that increase blood glucose then the drug should be totally avoided. It is worth noting, however that the mineralocorticoid effects of Prednisone Deltasone are very minor. It is for this reason that it is not used in the management of adrenal-insufficiency unless it is followed with the administration of mineralocorticoid of higher potent. Some of the other short term side effects include insomnia, euphoria, and, rarely, mania and Long-term side-effects.
The side effects which can occur on long term are the weight gain, osteoporosis, diabetes mellitus type II, Cushing's syndrome, glaucoma and depression caused due to withdrawals.
Some of the major side effects are increased blood sugar for diabetics, weight gain, facial swelling, depression, mania, or other psychiatric symptoms such as unusual fatigue or weakness, mental confusion, blurred vision, abdominal pain, peptic ulcer, painful hips or shoulders, osteoporosis, insomnia and others and some of the minor side effects are stretch marks, nervousness, acne, rash, increased appetite, hyperactivity, frequent urination and diarrhea.
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