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Coronary heart disease is a severe cardiovascular disorder reported to be the single leading cause of deaths worldwide. Hypercholesterolemia, often referred to as high levels of cholesterol, is one of major risk factors of coronary heart disease. Rosulip-F is a medication that decreases levels of the so-called "bad" cholesterol and increases levels of the "good" one this way reducing the risk of developing the disease, which despite the overall gravity is fully treatable and preventable.
Rosulip-F is a HMG-CoA reductase inhibitor. Generally, this group of medications is known as statins. These have proved to be effective in eliminating major risks associated with coronary heart disease and not only. Thus, in terms of the effect produced, Rosulip-F lowers the risk of stroke and/or heart attack or any other (heart) complications in people that are in the risk group due to coronary heart disease, diabetes or other risk factors. In terms of the mechanism employed, it decreases concentrations of low-density lipoprotein cholesterol (LDL-C) and triglycerides in the blood on the one hand and increases concentrations of high-density lipoprotein cholesterol (HDL-C) on the other; the latter removes its bad counterpart from your blood and takes it back to your liver.
Recommendations for Use
Rosulip-F (a film-coated pill) is:
• comprised of two major ingredients: rosuvastatin and fenofibrate BP
• produced in two dosage forms: rosuvastatin + fenofibrate BP in 5 mg/145 mg and 10 mg/145 mg respectively
The dosage is strictly individualized and the medication is taken orally exactly as indicated. Initially, this can be either 5 mg or 10 mg taken once a day. If required, the initial dosage can be increased at intervals to 20 and even 40 mg, where the latter is a maximum one. It should be remembered that, though the drug is a potent medication, it is still used as a part of an entire cholesterol management program together with a healthy diet, exercises and a healthy lifestyle on the whole.
Precautions and Contraindications
Before your doctor prescribes Rosulip-F you should inform him/her about a history of allergic reactions to statins. If there has been none, your doctor should know whether you have any of the following diseases as they are contraindications for treatment with Rosulip-F: heart disease, active liver or kidney disease, underactive thyroid and some other related conditions.
Additionally, contraindications include alcohol abuse and simultaneous intake with such medications as gemfibrozil, fenofibrate, cyclosporine, warfarin, cholestyramine, colestipol, high-dose niacin and some others. Birth control pills and antacids as well as herbal products are also subject to the doctor's approval so that no side effect could affect the treatment.
Generally, side effects are the result of an individual response in each particular case; however, a patient must strictly follow doctor's instructions to reduce the risk of development of any of the following undesirable reactions:
• Serious allergic reactions like dizziness, trouble breathing, swelling, rash, itching and some others like stomach/abdominal pain, vomiting, severe nausea, yellowing of the eyes and skin, dark urine or change in its amount require immediate medical attention
• Other possible side effects may include some muscle pain, headache, constipation, fatigue, cough, forgetfulness, confusion. Generally, these do not require immediate withdrawal unless they become persistent or bothering.
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