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Seroflo (Fluticasone Salmeterol)


Seroflo is a combined medical product containing Salmeterol and Fluticasone.

Seroflo provides antiasthmatic, bronchodilating, anti-inflammatory action. A regular use of Seroflo lowers the probability of bronchospasm, improves the respiratory function of lungs and lowers the probability of the aggravation of the bronchial asthma symptoms. Therapeutic effect of Seroflo is conditioned by the action of two active ingredients.

Fluticasone is a typical glucocorticosteroid which prevents the development of bronchospasm. It has an expressed anti-inflammatory and anti-allergic action reducing the sensitivity of the respiratory system to the external irritants.

Salmeterol is agonist of beta-adrenoceptors of the prolonged action. It improves the respiratory function of lungs, reduces the inflammatory processes, and relieves breathing. The prolonged action of this ingredient increases the action of corticosteroids causing more stable control of the respiratory system function.

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Directions for the use

Seroflo is prescribed adults and children older than 4 years old to prevent and treat:

- Reversible obstructive airway disease

- Chronic bronchial asthma

Seroflo may be prescribed patients who take only bronchodilators and are indicated corticosteroid therapy to increase the therapeutic effect


Seroflo is recommended for the prolonged everyday use even during the absence of the expressed symptoms of the respiratory system dysfunction.

At the beginning of the treatment, patients are prescribed the optimal dosage of fluticasone salmeterol which may be changed only by the doctor?s intention.

- Patients above 12 years of age are prescribed 1-2 inhalations 2 times a day

- Patients at the age of 4 to 12 years are recommended to take not more than 1 inhalation 1-2 times a day

- The active ingredients of fluticasone salmeterol are not absorbed in the systemic blood flow, and therefore senior patients, and patients with chronic diseases of liver and kidneys do not require the dosage adjustment.

- The duration of the treatment is indicated individually on the basis of the clinical image and therapeutic efficiency of Seroflo.

Seroflo is positioned as a bronchodilator of the prolonged action and does not work for the urgent arresting of spasms of the respiratory system. Therefore, using Seroflo inhaler, it is necessary to have inhalative bronchodilators of the short-term action which may arrest acute conditions of the bronchial asthma. Despite the overdose with Seroflo drug is hardly probable, it is pointless to have 4 inhalations a day. It will not increase the efficiency of the drug because the maximal concentration of the active ingredients is gained in the airways for 12 hours during the use of 2 inhalations.

In case of the high sensitivity to the active ingredients of the drug, the overdose with Seroflo may lead to the acute spasm of the respiratory tracts. That is why, to provide the high safety of the antiasthmatic therapy the dosage regimen and treatment adjustment should be made in case of the high sensitivity to the Seroflo ingredients.

Side effects

Potential side effects during the use of fluticasone salmeterol have a weak intensity. As a rule, the side effects are started during the first days of the treatment and last for just 3-5 days.

The most common side effects of Seroflo are:

- Irritation of the mucous membrane of the mouth cavity and throat

- Hoarseness

- Headache

- Light tremor

- Light edema in the lower part of face and mouth cavity

Systemic side effects of Seroflo are hardly probable because neither Salmeterol, nor Fluticasone are observed in the systemic blood flow. However, in case of the individual peculiarities of the body and intolerance of one of the active ingredients, the patient may develop such Seroflo side effects as:

- Sleep disorder

- Muscle cramps

- Glaucoma

- Disorder of the heart beat

- Heart hurry

One should see a doctor and adjust the scheme of the use/dosage of Seroflo during these side effects.

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