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Serophene (Clomiphene)


Itís a non-steroidal medication taken to increase fertility because it works by causing your pituitary gland to release the hormones necessary to stimulate proper ovulation or release of eggs from ovaries. These days, there are many female patients who take Serophene to treat a number of specific medical conditions, including polycystic ovary syndrome, because they prevent their ovulation to occur in a natural way.

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As a patient, you should know that a recommended dose of Serophene is 50 mg Ė 100 mg that must be taken orally for no longer than five days. Your initial dosage is most likely to be 50 mg, and your doctor may increase it based on your individual response to this treatment. This therapy can be repeated only 30 days after the previous one. Your physician must perform certain medical tests to ensure that you donít have any health conditions that may prevent you from using Serophene in a safe manner. Be sure to start this treatment on the fifth day of the menstrual period and follow all the instructions given by your doctor. Itís necessary to undergo a pelvic examination before you start taking this medication and you need to remain under the control of a doctor during the whole treatment. Most likely, youíre going to ovulate within 5-10 days after taking Serophene, but donít forget to take a temperature every morning and record these readings in a special chart. This medication must be stored at a room temperature and away from light, heat or moisture, and itís not advisable to overdose it or miss a dose.

Precautions and Contraindications

First, itís not allowed to take this medication if youíre already pregnant. If you have allergic reactions to its active ingredients, tumors, thyroid or adrenal gland disorders, liver problems, ovarian cyst, and abnormal vaginal bleeding, you shouldnít use Serophene. To ensure that its intake is 100% safe for you, itís necessary to inform your doctor if you have uterine fibroids or endometriosis. Donít forget that this medicine may cause harm to nursing babies because it passes into the breast milk. Another important detail is that using it for longer than three cycles can increase the risk of having an ovarian tumor. Besides, this treatment may boost your chance of developing multiple births.

Drug Interactions

There are certain pharmaceutical products that may interact with Serophene, thus, changing the way it works or increasing the risk of developing serious adverse effects. Thatís why you need to inform your doctor about other prescription and over-the-counter drugs that youíre taking in addition to herbal supplements, such as vitamins and minerals. For example, Gonadorelin is one of those meds that interact with this medication.

Side Effects

The intake of Serophene may result in blurred vision, and thatís why you should be careful when driving a car or doing other activities that require your full alertness. You need to go to the hospital once you notice any signs of allergic reactions to its active ingredients, including swelling, hives and trouble breathing. In very rare cases, female patients may develop OHSS, especially after their first treatment. Some of the most serious adverse effects associated with Serophene include vision problems, increased sensitivity of the eyes to light, pelvic pressure and enlargement, seeing flashes, vaginal bleeding, etc. The most common side effects include mild headaches, flushing, breakthrough spotting or bleeding, breast tenderness and pain and so on.

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