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Trivastal (Piribedil)


Dementia is a serious disorder of higher nervous activity, caused by organic brain damage, and manifests itself, in the first place, a sharp decline in mental abilities. The clinical picture of dementia depends on the cause of organic brain damage, the localization and extent of the defect, as well as the initial state of the organism. However, for all cases, dementia is characterized by persistent disorder, expressed the highest intellectual activity (memory impairment, reduced ability to abstract thinking, creativity and education), as well as more or less severe disorders of emotional and volitional, accentuation of traits (so-called "caricaturing") to complete disintegration of the personality.

Trivastal is effective treatment of dementia, as well as other vascular and traumatic diseases of the inner ear, Meniere's disease, post-traumatic vertigo, etc.

Application of Trivastal substance

Trivastal is used as an additional symptomatic therapy for chronic cognitive impairment and neurosensory deficit in the aging process (including disorders of attention and memory), Parkinson's disease (as monotherapy - in forms, mostly accompanied by tremor, or in combination therapy with levodopa - both the initial and later stages of the disease, especially in forms including tremor), as adjunctive therapy for symptomatic intermittent claudication due to occlusive arterial disease of the lower extremities (II stage classification Leriche and Fontaine); therapy symptoms of ophthalmic diseases, ischemic (including reduced visual acuity, reducing the color contrast).

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Contraindications of Trivastal and possible side effects

Among contraindications, which are listed in Trivastal prescription are hypersensitivity, hypotension, collapse, myocardial infarction (acute phase), co-administration with antipsychotics with pronounced antipsychotic properties (except clozapine), pregnancy, lactation. Actually, this list of precautions is common for many other medications and should be taken into consideration.

Trivastal medication is contraindicated in pregnancy (adequate and well-controlled studies on the use during pregnancy has not been done) and during lactation.

Anxiety, agitation, drowsiness, mental disorders, orthostatic hypotension, nausea, vomiting, flatulence - can be caused by the main substance of Trivastal while or after treatment course. But there is nothing dangerous as all these conditions pass quickly after withdrawal of the drug.

Dosing and administration of Trivastal is appointed by your treatment doctor. After careful monitor of your disease and overall health condition, he will pick up the correct dose, which will be effective and safe in your particular case. If you read in prescription, you will find common doses in all cases. Thus, Trivastal is taken inside with the food, 50 mg / day at a time, if necessary, 50 mg 2 times a day. Parkinson's disease: monotherapy - 150-250 mg / day in 3-5 receptions, and in combination with levodopa - 100-150 mg in 2-3 doses.

Clinic analysis of Trivastal application efficacy in the treatment of Parkinson's disease

Parkinson's disease (PD) - one of the most common chronic neurodegenerative diseases, caused by progressive loss of dopamine-containing cells of certain pathway. Over the last decade, with new dopamine receptor agonists the principles of treatment of PD significantly mutated. Trivastal is still the most effective treatment for PD.

It has been shown that the drug affects all the major symptoms of Parkinson largely tremor and also reduces the severity of depression. The positive impact of Trivastal is shown on cognitive disorders. The data has shown clinical efficacy, safety and clinical evidence of economic feasibility of this medication in patients with Parkinson's disease in clinical practice.

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