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Zestril (Lisinopril)


Zestril is a brand name for a drug that belongs to ACE inhibitors. Its generic name is Lisinopril. It is mostly used for treatment of CHF, hypertension and may also be prescribed for faster recovery after having a heart attack.

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Recommendations for Use

Zestril should only be taken as prescribed by your healthcare provider. The dosage may be changed by your doctor occasionally for a better result. It is dangerous to change the dosage of Zestril or the length of its use without consulting a doctor. The medication is taken once a day. The dosage for a particular patient is determined by a doctor based on many factors, including the presence of other health problems and severity of the disease.

While taking Zestril, it is recommended to drink water often during a day, however, the drug can be administered regardless of taking food. In order to control the effectiveness of Zestril, your blood pressure should be checked regularly and sometimes blood tests should be taken as well. If any side effect occurs, notifying a doctor is very important. If Zestril is prescribed for a patient with hypertension, no pausing or stopping should take place even if a patient feels much better. In order to avoid feeling dizzy, a person taking Zestril should not get up too fast from any position. It is better to stand up slowly.

The drug should be stored away from heat.

Precautions and Contraindications

There is a range of precautions and contradictions that should be learnt before using this drug.

Zestril should not be taken in the following cases:

• If a patient has HAE;
• In case of allergy to any other ACE inhibitors, including ramipril, fosinopril, moexipril, trandolapril, perindopril, and others;
• If a patient has diabetes and uses other drugs with aliskiren;
• During pregnancy (if a woman finds out about pregnancy while taking Zestril, she should stop doing that and notify a doctor about it immediately);
• If a woman is breast-feeding.

In order to use Zestril the following information should be provided to a doctor:

• If a patient has any kidney disease;
• If a patient has diabetes;
• If a patient has any liver disease;
• If potassium levels in patient’s blood are too high;
• If a patient needs a surgery, he or she should notify their surgeon about taking Zestril.
Generally, it is recommended to avoid using alcohol as this may decrease the effectiveness of taking Zestril and increase the risk of experiencing side effects.

Drug Interactions

There are 659 known meds that may interact with Zestril. Among them, 79 are major drug interactions, including the following:

• Aldactazide;
• Aliskiren;
• Alka-Seltzer Gold;
• Aloprim;
• Amiloride;
• Aminophylline, etc.

That is why it is important to consult a doctor first before taking any other drugs with Zestril.

Side Effects

Zestril may cause side effects that differ by severity. A patient should look for urgent medical help if he/she experiences at least one of these side effects:

• Problems with urinating (little or no urinating; pain when urinating; dark urine);
• Problems with movement;
• Any allergic reactions like hives, pain in the stomach, problems breathing, some swelling in the body;
• Decreasing appetite;
• Feeling like losing consciousness;
• Unusual heart rate;
• Vomiting;
• Jaundice;
• Nausea;
• Diarrhea;
• Unusual stools.

The following are common side effects after taking Zestril:

• Dizziness;
• Pain in chest;
• Headache;
• Cough.

Any other side effects that may occur should prompt patients to immediately consult their doctors as any delay may eventually lead to negative consequences.

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